Effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients

  • Ferinauli Ferinauli Mental Health Nursing Department, Binawan University, Jakarta, Indonesia.
  • Sari Narulita | sari@binawan.ac.id Mental Health Nursing Department, Binawan University, Jakarta, Indonesia.
  • Yoanita Hijriyati Basic Nursing Department, Binawan University, Jakarta, Indonesia.


Background: Management of schizophrenia using psychopharmaceuticals requires a long-term treatment. The use of antipsychotic drugs can cause the occurrence of orthostatic hypotension, which leads to the risk of falling in patients. The aim of this study is to determine the effect of the use of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients.
Design and Methods: This study used a descriptive design with 53 respondents. Data were analyzed using the contingency coefficient correlation and Spearman Rank test methods.
Results: The results of the first study showed no positive effect between the use of antipsychotics on orthostatic hypotension in schizophrenic patients. In addition, a contingency coefficient correlation (C) of 0.199 and p-value of 0.335 (p>0.05) was obtained. The results of the second study showed that there was a significant positive effect between orthostatic hypotension on the risk of falling in schizophrenic patients with a value of r = 0.483 and a p-value of 0.000 (p<0.001).
Conclusion: It was suggested that the development of this study’s result is needed for further research in dealing with the incidence of orthostatic hypotension in order to prevent or reduce the risk of falling in schizophrenic patients.



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Ethics Approval
This study has been approved by the health research ethics committee of the Binawan University Jakarta and Dr. H. Marzoeki Mahdi Hospital Bogor
Antipsychotics drugs, orthostatic hypotension, fall risk
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How to Cite
Ferinauli, F., Narulita, S., & Hijriyati, Y. (2021). Effect of antipsychotic drugs and orthostatic hypotension on the risk of falling in schizophrenic patients. Journal of Public Health Research, 10(2). https://doi.org/10.4081/jphr.2021.2184